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Education

11/2005 – 11/2010: PhD in Medical Sciences (Radboud University Nijmegen), cum laude

Title: Cerebral reorganization in Parkinson’s disease
Supervisors: Prof. Dr. I. Toni & Prof. Dr. B.R. Bloem

9/1998 – 11/2005:   Medicine (Radboud University Nijmegen), cum laude

9/1992 – 7/1998:     High school (Vechtdal college, Hardenberg), cum laude

Professional Experience

11/2010 – now:       Resident in Neurology (Radboud University Medical Centre, Neurology Department)

11/2012 – 4/2016:   Post-doctoral fellow (Radboud University Medical Centre, Donders Institute for Brain, Cognition and Behaviour; 0.4 fte)

4/2015 – 8/2015:    Research fellow (National Institutes of Health, National Institute of Neurological Disorders and Stroke, Human Motor Control Section (chief: Dr. M. Hallett), Bethesda, MD, USA)

11/2005 – 11/2010: PhD student (Radboud University Nijmegen, Donders Institute for Brain, Cognition and Behaviour and Neurology department

Grants

2016:                   NWO VENI (€ 250.000). The noradrenergic basis of Parkinson’s tremor: a systems-level fMRI approach. Role: project leader.

2016:                   Dutch Brain Foundation, Benny Vleerlaag Fonds (€ 105.000). The cerebral mechanisms underlying dyston¡c and essential tremor: a multimodal network approach. HA2016-02-01. Role: project leader.

2016:                   NWO Off Road (€ 125.000). Precision neuroscience for precision neurology: guiding personalized treatments for Parkinson’s tremor with individual neuroimaging. Role: project leader.

2016:                   Prinses Beatrix Fonds (€ 249.853). How transient peripheral dysfunction leads to long-lasting maladaptive plasticity in the central nervous system: a randomized controlled trial in neuralgic amyotrophy. Role: co-applicant & co-project leader (with Dr Van Alfen and Dr Groothuis).

2013:                    Dutch Brain Foundation (€ 150.000). Why Parkinson’s disease has a variable dopaminergic response – cerebral differences between dopamine-responsive and dopamine-resistant tremor. F2013(1)-15. Role: project leader.

2013:                    Van Leersum Fonds (€ 6.800). Multitasking in Parkinson’s disease: cerebral mechanisms of a pervasive and fundamental impairment. VLF2013229.  Role: project leader.

Prizes

2012:                    Prinses Beatrix Fonds Jaarprijs Bewegingsstoornissen (€1000)
2012:                    Dutch Neurofederation PhD Thesis Prize (€2000)
2011:                    Susanne Klein-Vogelbach Prize (CHF 10 000)
2009:                    Movement Disorders Society (travel award; $1000)

Research mission

In my research, I aim to understand the functional anatomy of movement disorders using advanced neuroimaging. Examples of common movement disorders are Parkinson’s disease, dystonia, and tremor. These disorders are linked to functional changes in motor and cognitive cerebral circuits. As a clinician and neuroscientist, I hope to contribute to this field by focusing on the interplay between clinical symptoms and basic models of motor and cognitive control. I am convinced that expertise in both areas is necessary for asking innovative questions that are clinically relevant, while mastering the methods required to empirically test these questions.

Attention in the press

  • Parkinsonpatient trilt soms door overijverig brein. Volkskrant, 25-03-2011.
  • Beloning bij Parkinson leidt tot mobiliteit. Gelderlander, 18-06-2011.
  • Onderzoek naar Parkinson met fMRI. Neurology News International, August 2011.
  • TV Nijmegen, 30-03-2011.
  • Schakelaar in hersenen laat parkinsonpatient trillen. Nu.nl, 25-03-2011.

Publications

CV

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